CRi Maestro systems now feature increased multiplexing capability and even better low light-level sensitivity. Their unique technology allows higher spectral accuracy and improved signal separation. Maestro systems are breakthrough instruments for fluorescence-based in-vivo molecular imaging. Using multispectral acquisition and analysis, they provide dramatically improved sensitivity, multicolor flexibility and quantitative accuracy for both visible and near-infrared labels.

Autofluorescence-unwanted light emission from unlabeled tissues that can obscure all but the brightest of signals-limits the usefulness of conventional in-vivo fluorescence imaging. Expensive cameras do not help, since they simply capture both the autofluorescence and the desired fluorescence signal more efficiently. Maestro systems employ unique multispectral imaging technology to virtually eliminate autofluorescence, revealing otherwise invisible labeled targets-that now appear bright against a near-black background. This dramatic improvement in signal-to-noise can increase sensitivity many fold, allowing much smaller or fainter targets to be detected.

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The IVIS Imaging System is a highly sensitive and large field of view imaging system that offers users the flexibility to image fluorescent and/orbioluminescent reporters both in vivo and in vitro. It relies on patented optical imaging technologies to facilitate non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.

The IVIS offers an adjustable field of view of 10-25 cm, allowing 5 mice or 2 large rats to be imaged. The system features a 25 mm (1.0 inch) square back-thinned, back-illuminated CCD, which is cryogenically cooled to –90°C via a closed cycle refrigeration system (without liquid nitrogen) to minimize electronic background and maximize sensitivity. A patented and extremely light-tight, low background imaging chamber allows the IVIS to be used in standard lab lighting environments. The system includes animal handling features such as a heated sample shelf, gas anesthesia connections, and an optional full gas anesthesia system. The IVIS Imaging System is highly automated with all hardware motor movement, imaging parameters, and image analysis controlled via Living Image® software.

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The Leica Dissection scope is ideal for GFP, DS-RED, and other labeling in animals. This scope can also image objects from 10cm to 1cm.

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